Can MS Symptoms Fluctuate Throughout the Day?

MS symptoms might change during the day, including fatigue and stiffness in the muscles. In a relapse, they may also fluctuate for several days or weeks. However each person's experience of how the symptoms evolve can be very different.

Progressive MS is an immune-mediated illness. It can cause harm to multiple brain and spinal cord regions, resulting in a wide range of erratic symptoms.

The intensity of certain MS symptoms can change throughout the day. Remember that your experience could not be the same as someone else's.

Do MS symptoms fluctuate throughout the day?

You're not alone if you think your MS symptoms improve or worsen throughout the day. The intensity of MS symptoms might fluctuate throughout the day.

Experts and academics frequently concentrate on broad patterns of symptoms over several months or years. Studies, however, have concentrated on specific symptoms over the day or for shorter durations of time.

Researchers discovered evidence in a 2017 study to support the theory that fatigue in individuals with relapsing-remitting MS can vary for the same reasons that fatigue in healthy individuals varies.

Stress, emotional swings, sleep deprivation, temperature changes, and other factors can all contribute to variations.

The effects of physical activity on MS fatigue vary. Fatigue can occasionally be triggered or brought on by physical activity, but consistent moderate exercise can assist increase stamina, strength, and endurance.

Eighty percent of MS patients are expected to have spasticity. Muscle stiffness that can cause spasms, discomfort, and decreased mobility is known as spasticity. Movement usually makes spasticity worse or more obvious.

Additionally, it could precipitate or exacerbate other symptoms like exhaustion, insomnia, and bladder problems. When you lay down to sleep at night or in the evening, you could notice that certain of your MS symptoms get worse.

Remember that multiple sclerosis (MS) is a very varied illness that affects people differently and to varying degrees. Your symptoms may get better at night and get worse in the morning or midafternoon.

What are the symptoms that worsen during the day?

It is estimated that 65–80% of MS patients experience fatigue. The fatigue that comes with multiple sclerosis usually gets worse after physical activity. This indicates that among those with MS, it frequently happens throughout the day.

It might also rise as a result of regular, everyday variations in stress and mood. Taking action to lessen stress at home, at work, or in school may help prevent weariness during the day.

During the day, other symptoms could also get worse. Typical MS symptoms that you can experience worsening or becoming more apparent during the day include:
  • bladder and bowel problems
  • numbness and tingling
  • tremor
  • pain
  • vision issues
  • difficulties remembering and thinking
  • tense, stiff, spastic, or spasmic muscles
  • imbalance issues and lightheadedness
You could or might not experience any of these symptoms during the day, as the severity of the symptoms varies widely among individuals.

How often do MS symptoms come and go?

MS is linked to either a gradual increase in the severity and development of symptoms or intervals of disease activity (relapse) interspersed with intervals in which symptoms either completely or mostly disappear.

If you have relapsing-remitting multiple sclerosis, you might observe that your symptoms during a relapse include:
  • begin suddenly in a few days or hours.
  • attain a peak in a few days.
  • if the relapse is treated, gradually improve over the next few days or weeks.
Even with treatment, symptoms might occasionally persist for eight weeks or more.

Multiple sclerosis symptoms might arise due to many reasons. Among the factors influencing symptoms are:
  • age
  • gender
  • infections
  • pregnancy
  • Vitamin D levels in serum (amount in the blood)
  • temperature: It is recognised that heat exacerbates MS symptoms.
In addition to these factors, smoking, stress, some drugs, and exposure to heat or cold can also cause symptoms. Once the trigger is eliminated, the symptoms could go away.


The intensity of MS symptoms might fluctuate throughout the day. Some may appear more frequently at night, while others may appear more frequently during the day.

It's difficult to generalise about MS. While many people report feeling exhausted during the day and having twitchy muscles at night, this may not be the case for everyone. The intensity of your symptoms could not alter, or you might find that they change regularly throughout the day.

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